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As a result, more and more companies are looking to include non-traditional yet potentially very valuable data with their traditional enterprise data in their business intelligence analysis. To derive real business value from big data, you need the right tools to capture and organize a wide variety of data types from different sources, and to be able to easily analyze it within the context of all your enterprise data. Oracle offers the broadest and most integrated portfolio of products to help you acquire and organize these diverse data types and analyze them alongside your existing data to find new. | OPEN 3 ACCESS Freely available online PLPS genetics The Genographic Project Public Participation Mitochondrial DNA Database Doron M. Behar1 2 Saharon Rosset3 Jason Blue-Smith4. Olea Balanovskv5. Shay Tzur1 David Comas6. R. John Mitchell7 B B B B B B B B B . B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B B . B B BBBB BBBB B B B B B B B Lluis Quintana-Murci8 9 Chris Tyler-Smith10 R. Spencer Wells4 The Genographic Consortium 1 Genomics Research Center Family Tree DNA Houston Texas United States of America 2 Molecular Medicine Laboratory Rambam Health Care Campus Haifa Israel 3 Data Analytics Research Group IBM T. J. Watson Research Center Yorktown Heights New York United States of America 4 The Genographic Project National Geographic Society Washington District ofColumbia United States ofAmerica 5 Research Centre for Medical Genetics Russian Academy of Medical Sciences Moscow Russia 6 Unitat de Biologia Evolutiva Universitat Pompeu Fabra Barcelona Spain 7 Department of Genetics La Trobe University Bundoora Australia 8 Institut Pasteur Paris France 9 CNRS URA3012 Paris France 10 The Wellcome Trust Sanger Institute Wellcome Trust Genome Campus Hinxton Cambridge United Kingdom The Genographic Project is studying the genetic signatures of ancient human migrations and creating an open-source research database. It allows members of the public to participate in a real-time anthropological genetics study by submitting personal samples for analysis and donating the genetic results to the database. We report our experience from the first 18 months of public participation in the Genographic Project during which we have created the largest standardized human mitochondrial DNA mtDNA database ever collected comprising 78 590 genotypes. Here we detail our genotyping and quality assurance protocols including direct sequencing of the mtDNA HVS-I genotyping of 22 coding-region SNPs and a .
