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Evpidemiologic heterogeneity of common mood and anxiety disorders over the lifecourse in the general population: a systematic review | BMC Psychiatry BioMed Central Research article Open Access Epidemiologic heterogeneity of common mood and anxiety disorders over the lifecourse in the general population a systematic review Arijit Nandi1 John R Beard2 3 4 and Sandro Galea 2 5 6 7 Address Center for Population and Development Studies Harvard School of Public Health Boston USA 2Center for Urban Epidemiologic Studies New York Academy of Medicine New York USA 3School of Public Health University of Sydney Sydney Australia 4Faculty of Health and Applied Science Southern Cross University Lismore Australia 5Department of Epidemiology University of Michigan School of Public Health Ann Arbor USA 6Department of Epidemiology Columbia University Mailman School of Public Health New York USA and 7Survey Research Center Institute for Social Research Ann Arbor USA Email Arijit Nandi - anandi@hsph.harvard.edu John R Beard - jbeard@nyam.org Sandro Galea - sgalea@umich.edu Corresponding author Published I June 2009 Received II November 2008 BMC Psychiatry 2009 9 31 doi 10.1186 1471-244X-9-3 1 Accepted 1 June 2009 This article is available from http www.biomedcentral.cOm 1471-244X 9 31 2009 Nandi et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Clinical evidence has long suggested there may be heterogeneity in the patterns and predictors of common mood and anxiety disorders however epidemiologic studies have generally treated these outcomes as homogenous entities. The objective of this study was to systematically review the epidemiologic evidence for potential patterns of heterogeneity of common mood and anxiety disorders over the lifecourse in the general population. Methods We reviewed epidemiologic studies examining heterogeneity in either the nature
