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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Timeliness of administration of vasopressors in CPR. | Available online http ccforum.eom content 13 1 401 Letter Timeliness of administration of vasopressors in CPR Stefek Grmec and Stefan Mally Center for Emergency Medicine Maribor Ulica talcev 9 Maribor 2000 Medical Faculty University Maribor Medical Faculty University Ljubljana Faculty for Health Sciences University Maribor Slovenia Corresponding author Stefek Grmec grmec-mis@siol.net Published 28 January 2009 Critical Care 2009 13 401 doi 10.1186 cc7691 This article is online at http ccforum.com content 13 1 401 2009 BioMed Central Ltd We read with great interest the report by Gueugniaud and coworkers 1 on the role of combined vasopressin and epinephrine during advanced cardiac life support for out-ofhospital cardiac arrest. The authors conclude that the combination does not improve outcome. In some of our previous studies 2 3 we identified improvements in restoration of spontaneous circulation ROSC and or survival and neurological outcome when combining vasopressors to manage out-of-hospital cardiac arrest and therefore we were surprised by the results of this study. In our study 2 we showed that combined vasopressor treatment increased end-tidal carbon dioxide and mean arterial pressure values during cardiopulmonary resuscitation CPR and consequently improved ROSC short-term survival and neurological outcome. Additionally improved hospital discharge was observed in the subgroup of patients with initial asystole. In a previous study 3 we identified a significantly higher hospital discharge rate in the subgroup of patients with acute myocardial infarction as the underlying cause of ventricular fibrillation when vasopressin was used during CPR. In our opinion the differences in findings between our studies 2 3 and that by Gueugniaud and coworkers 1 result partly from use of different methodology and partly from differences in population characteristics. In the study by Gueugniaud and coworkers 1 the average arrival time of the advanced cardiac life support team and
