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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Protocol for a randomised controlled trial investigating the effectiveness of an online e health application for the prevention of Generalised Anxiety Disorder | Christensen et al. BMC Psychiatry 2010 10 25 http www.biomedcentral.com 1471-244X 10 25 BMC Psychiatry STUDY PROTOCOL Open Access Protocol for a randomised controlled trial investigating the effectiveness of an online e health application for the prevention of Generalised Anxiety Disorder Helen Christensen1 Kathleen M Griffiths1 Andrew J Mackinnon2 Kanupriya Kalia1 Philip J Batterham1 Justin Kenardy3 Claire Eagleson4 Kylie Bennett1 Abstract Background Generalised Anxiety Disorder GAD is a highly prevalent psychiatric disorder. Effective prevention in young adulthood has the potential to reduce the prevalence of the disorder to reduce disability and lower the costs of the disorder to the community. The present trial the WebGAD trial aims to evaluate the effectiveness of an evidence-based online prevention website for GAD. Methods Design The principal clinical question under investigation is the effectiveness of an online GAD intervention E-couch using a community-based sample. We examine whether the effect of the intervention can be maximised by either human support in the form of telephone calls or by automated support through emails. The primary outcome will be a reduction in symptoms on the GAD-7 in the active arms relative to the non active intervention arms. Discussion The WebGAD trial will be the first to evaluate the use of an internet-based cognitive behavioural therapy CBT program contrasted with a credible control condition for the prevention of GAD and the first formal RCT evaluation of a web-based program for GAD using community recruitment. In general internet-based CBT programs have been shown to be effective for the treatment of other anxiety disorders such as Post Traumatic Stress Disorder Social Phobia Panic Disorder and stress in clinical trials however there is no evidence for the use of internet CBT in the prevention of GAD. Given the severe shortage of therapists identified in Australia and overseas and the low rates of treatment seeking in .