Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ
Tải xuống
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Cost-effectiveness of continuous glucose monitoring and intensive insulin therapy for type 1 diabetes. | McQueen et al. Cost Effectiveness and Resource Allocation 2011 9 13 http www.resource-allocation.eom content 9 1 13 COST EFFECTIVENESS AND RESOURCE ALLOCATION RESEARCH Open Access Cost-effectiveness of continuous glucose monitoring and intensive insulin therapy for type 1 diabetes R Rrott Madi loom 1 t irsl I Pllic2t n c amr l oll1t M úl 1t putrid A Cl illi ìrì3t R Biett IVUQUeell Samuel L Ellis Jondthdn D Cdllipuell Kdvitd V INdil dnd Pdtlick W Sullivdn Abstract Background Our objective wds to determine the cost-effectiveness of Continuous Glucose Monitoring CGM technology with intensive insulin therdpy compdred to self-monitoring of blood glucose SMBG in ddults with type 1 didbetes in the United Stdtes. Methods A Mdrkov cohort dndlysis wds used to model the long-term disedse progression of 12 different didbetes disedse stdtes using d cycle length of 1 yedr with d 33-yedr time horizon. The dndlysis uses d societdl perspective to model d populdtion with d 20-yedr history of didbetes with medn dge of 40. Costs dre expressed in US 2007 effectiveness in qudlity-ddjusted life yedrs QALYs . Pdrdmeter estimdtes dnd their ranges were derived from the literature. Utility estimdtes were drawn from the EQ-5D cdtdlogue. Probdbilities were derived from the Didbetes Control dnd Complicdtions Tridl DCCT the United Kingdom Prospective Didbetes Study UKPDS dnd the Wisconsin Epidemiologic Study of Didbetic Retinopdthy. Costs dnd QALYs were discounted dt 3 per yedr. Univdridte dnd Multivdridte probdbilistic sensitivity dndlyses were conducted using 10 000 Monte Cdrlo simuldtions. Results Compdred to SMBG use of CGM with intensive insulin tredtment resulted in dn expected improvement in effectiveness of 0.52 QALYs dnd dn expected incredse in cost of 23 552 resulting in dn ICER of dpproximdtely 45 033 QALY. For d willingness-to-pdy WTP of 100 000 QALY CGM with intensive insulin therapy wds costeffective in 70 of the Monte Cdrlo simuldtions. Conclusions CGM with intensive insulin .