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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: The impact of provider-initiated (opt-out) HIV testing and counseling of patients with sexually transmitted infection in Cape Town, South Africa: a controlled trial | Leon et al. Implementation Science 2010 5 8 http www.implementationscience.eom content 5 1 8 Implementation Science IMPLEMENTATION SCIENCE RESEARCH ARTICLE Open Access The impact of provider-initiated opt-out HIV testing and counseling of patients with sexually transmitted infection in Cape Town South Africa a controlled trial Natalie Leon1 Pren Naidoo2 Catherine Mathews1 3 Simon Lewin1 4 Carl Lombard5 Abstract Background The effectiveness of provider-initiated HIV testing and counseling PITC for patients with sexually transmitted infection STI in resource-constrained settings are of particular concern for high HIV prevalence countries like South Africa. This study evaluated whether the PITC approach increased HIV testing amongst patients with a new episode of sexually transmitted infection as compared to standard voluntary counseling and testing VCT at the primary care level in South Africa a high prevalence and low resource setting. Methods The design was a pragmatic cluster-controlled trial with seven intervention and 14 control clinics in Cape Town. Nurses in intervention clinics integrated PITC into standard HIV care with few additional resources whilst lay counselors continued with the VCT approach in control clinics. Routine data were collected for a six-month period following the intervention in 2007 on new STI patients who were offered and who accepted HIV testing. The main outcome measure was the proportion of new STI patients tested for HIV with secondary outcomes being the proportions who were offered and who declined the HIV test. Results A significantly higher proportion of new STI patients in the intervention group tested for HIV as compared to the control group with 56.4 intervention versus 42.6 control p 0.037 . This increase was achieved despite a significantly higher proportion intervention group declining testing when offered 26.7 intervention versus 13.5 control p 0.0086 . Patients were more likely to be offered HIV testing in intervention .