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Although this book is far from being exhaustive, it conveys some of the novel ideas and directions in the membrane trafficking field through a combination of review, research, and technical articles. The book is organized in a series of chapters that will “transport” the reader from the endoplasmic reticulum, where proteins and lipids are synthesized, to the plasma membrane, where molecules are either delivered or internalized via endocytosis. Some of the basic steps of the secretory pathway are here reviewed, such as the transport of cargo molecules from the ER to the Golgi apparatus, the sorting of transport intermediates at the Trans-Golgi Network, and the delivery of secretory. | GENETICS AND PATHOPHYSIOLOGY OF ESSENTIAL HYPERTENSION Edited by Madhu Khullar INTECHWEB.ORG Genetics and Pathophysiology of Essential Hypertension Edited by Madhu Khullar Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. As for readers this license allows users to download copy and build upon published chapters even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Dejan Grgur Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published March 2012 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Genetics and Pathophysiology of Essential Hypertension Edited by Madhu Khullar p. cm. ISBN 978-953-51-0282-3 INTECH open science I open minds free .