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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Formulas Vasopressin and epinephrine in the treatment of cardiac arrest: an experimental study. | Available online http ccforum.eom content 1 2 2 R40 Research Vasopressin and epinephrine in the treatment of cardiac arrest an experimental study Konstantinos Stroumpoulis Theodoros Xanthos Georgios Rokas Vassiliki Kitsou Dimitrios Papadimitriou loannis Serpetinis Despina Perrea Lila Papadimitriou and Evangelia Kouskouni University of Athens Medical School Department of Experimental Surgery and Surgical Research Agiou Thoma Street Athens Greece Corresponding author Theodoros Xanthos theodorosxanthos@yahoo.com Received 22 Oct 2007 Revisions requested 13 Dec 2007 Revisions received 4 Jan 2008 Accepted 1 4 Mar 2008 Published 14 Mar 2008 Critical Care 2008 12 R40 doi 10.1186 cc6838 This article is online at http ccforum.com content 12 2 R40 2008 Stroumpoulis et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 . which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Background Epinephrine remains the drug of choice for cardiopulmonary resuscitation. The aim of the present study is to assess whether the combination of vasopressin and epinephrine given their different mechanisms of action provides better results than epinephrine alone in cardiopulmonary resuscitation. Methods Ventricular fibrillation was induced in 22 Landrace Large-White piglets which were left untreated for 8 minutes before attempted resuscitation with precordial compression mechanical ventilation and electrical defibrillation. Animals were randomized into 2 groups during cardiopulmonary resuscitation 11 animals who received saline as placebo 20 ml dilution bolus epinephrine 0.02 mg kg Epi group and 11 animals who received vasopressin 0.4 IU kg 20 ml dilution bolus epinephrine 0.02 mg kg defibrillation was attempted fibrillation. Vaso-Epi group . Electrical after 10 minutes of ventricular .
