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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions. | Available online http ccforum.eom content 11 6 R130 Research Causes of metabolic acidosis in canine hemorrhagic shock role of unmeasured ions Dirk Bruegger1 Gregor I Kemming1 Matthias Jacob1 Franz G Meisner2 Christoph J Wojtczyk3 Kristian B Packert1 Peter E Keipert4 N Simon Faithfull5 Oliver P Habler6 Bernhard F Becker7 and Markus Rehm1 Open Access 1Clinic of Anesthesiology Ludwig-Maximilians-University Marchioninistrasse 15 81377 Munich Germany 2Department of Thoracic and Vascular Surgery University of Ulm Steinhovelstrasse 9 89075 Ulm Germany 3Department of General Visceral and Thoracic Surgery Clinic of Nuremberg Prof.-Ernst-Nathan-Strasse 1 90419 Nuremberg Germany 4Sangart Inc. 6175 Lusk Blvd. San Diego CA 92121 USA 5Alliance Pharmaceutical Corp. 4660 La Jolla Village Drive San Diego CA 921 22 USA 6Clinic of Anesthesiology Intensive Care Medicine and Pain Management Krankenhaus Nordwest Steinbacher Hohl 2-26 60488 Frankfurt Germany 7Department of Physiology Ludwig-Maximilians-University Pettenkoferstrasse 12 80336 Munich Germany Corresponding author Dirk Bruegger dirk.bruegger@med.uni-muenchen.de Received 14 Aug 2007 Revisions requested 28 Sep 2007 Revisions received 26 Nov 2007 Accepted 14 Dec 2007 Published 14 Dec 2007 Critical Care 2007 11 R130 doi 10.1186 cc6200 This article is online at http ccforum.com content 11 6 R130 2007 Bruegger et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Metabolic acidosis during hemorrhagic shock is common and conventionally considered to be due to hyperlactatemia. There is increasing awareness however that other nonlactate unmeasured anions contribute to this type of acidosis. Methods Eleven anesthetized dogs were hemorrhaged to a mean arterial pressure of
