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Báo cáo y học: " Determination of the threshold of cardiac troponin I associated with an adverse postoperative outcome after cardiac surgery: a comparative study between coronary artery bypass graft, valve surgery, and combined cardiac surgery"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Determination of the threshold of cardiac troponin I associated with an adverse postoperative outcome after cardiac surgery: a comparative study between coronary artery bypass graft, valve surgery, and combined cardiac surgery | Available online http ccforum.eom content 11 5 R106 Research Determination of the threshold of cardiac troponin I associated with an adverse postoperative outcome after cardiac surgery a comparative study between coronary artery bypass graft valve surgery and combined cardiac surgery Jean-Luc Fellahi1 Franpois Hedoire1 Yannick Le Manach2 Emmanuel Monier1 Louis Guillou1 and Bruno Riou3 Centre Hospitalier Privé Saint-Martin 18 rue des Roquemonts 1 4050 Caen Cedex 4 France 2Department of Anesthesiology and Critical Care CHU Pitié-Salpêtrière 47-83 boulevard de l Hopital 75013 Paris France 3Emergency Medical Department CHU Pitié-Salpêtrière 47-83 boulevard de l Hopital 75013 Paris France Corresponding author Jean-Luc Fellahi jean-luc.fellahi@gdsnb.gsante.fr Received 30 Apr 2007 Revisions requested 27 May 2007 Revisions received 31 Jul 2007 Accepted 21 Sep 2007 Published 21 Sep 2007 Critical Care 2007 11 R106 doi 10.1186 cc6126 This article is online at http ccforum.com content 11 5 R1 06 2007 Fellahi et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 20 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The objective of the present study was to compare postoperative cardiac troponin I cTnl release and the thresholds of cTnl that predict adverse outcome after elective coronary artery bypass graft CABG after valve surgery and after combined cardiac surgery. Methods Six hundred and seventy-five adult patients undergoing conventional cardiac surgery with cardiopulmonary bypass were retrospectively analyzed. Patients in the CABG n 225 and valve surgery groups n 225 were selected after matching age sex with those in the combined surgery group n 225 . cTnl was measured preoperatively and 24 hours after the end of surgery. The main endpoint was a severe