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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Percutaneous tracheostomy in patients with severe liver disease and a high incidence of refractory coagulopathy: a prospective trial. | Available online http ccforum.eom content 11 5 R110 Research Percutaneous tracheostomy in patients with severe liver disease and a high incidence of refractory coagulopathy a prospective trial Georg Auzinger Gerry P O Callaghan William Bernal Elizabeth Sizer and Julia A Wendon Institute of Liver Studies Liver Intensive Care Unit King s College Hospital Denmark Hill London SE5 9RS UK Corresponding author Georg Auzinger georg.auzinger@kingsch.nhs.uk Received 12 Apr 2007 Revisions requested 31 May 2007 Revisions received 10 Aug 2007 Accepted 8 Oct 2007 Published 8 Oct 2007 Critical Care 2007 11 R110 doi 10.1186 cc6143 This article is online at http ccforum.com content 11 5 R110 2007 Auzinger et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The purpose of this study was to assess the safety of percutaneous dilational tracheostomy PDT performed by experienced operators in critically ill patients with liver disease and coagulopathy. Methods We conducted a prospective cohort study in a 10-bed specialist liver intensive care unit of a tertiary university teaching hospital. The study consisted of 60 consecutive patients in need of tracheostomy insertion. Patients were categorized as having refractory coagulopathy if their platelet count was less than or equal to 50 X 109 cells L or their international normalized ratio INR was greater than 1.5 on the day of PDT and for the 72 hours afterward despite clotting support. Results Twenty-five patients fulfilled the definition criteria of refractory coagulopathy. There was no significant difference in the number of adverse incidents between groups. Only one patient in the coagulopathy group had a severe bleeding complication but this did not require .
