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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Impaired urge-to-cough in elderly patients with aspiration pneumonia. | Cough BioMed Central Open Access Impaired urge-to-cough in elderly patients with aspiration pneumonia Shinsuke Yamanda Satoru Ebihara Takae Ebihara Miyako Yamasaki Takaaki Asamura Masanori Asada Kaori Une and Hiroyuki Arai Address Department of Geriatrics and Gerontology Institute of Development Aging and Cancer Tohoku University Seiryo-machi 4-1 Aoba-ku Sendai 980-8575 Japan Email ShinsukeYamanda-debunda@hotmail.com Satoru Ebihara - sebihara@idac.tohoku.ac.jp Takae Ebihara - takae_montreal@hotmail.com Miyako Yamasaki - ymskmyk@idac.tohoku.ac.jp Takaaki Asamura -1-asamuraum777@silk.plala.or.jp Masanori Asada - m-asada@idac.tohoku.ac.jp Kaori Une - unekaori@hotmail.com Hiroyuki Arai - harai@idac.tohoku.ac.jp Corresponding author Published 19 November 2008 Received 30 July 2008 Accepted 19 November 2008 Cough 2008 4 11 doi 10.1186 1745-9974-4-11 p This article is available from http www.coughjournal.com contentM 1 1 1 2008 Yamanda et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The down-regulation of the cough reflex in patients with aspiration pneumonia can involve both cortical facilitator pathways for cough and medullary reflex pathways. In order to study the possible involvement of the supramedullary system in the down-regulation of cough reflex we evaluated the urge-to-cough in patients with aspiration pneumonia. Methods Cough reflex sensitivity and the urge-to-cough to inhaled citric acid were evaluated in patients with at least a history of aspiration pneumonia and age-matched healthy elderly people. The cough reflex sensitivities were defined as the lowest concentration of citric acid that elicited two or more coughs C2 and five or more coughs C5 . The urge-to-cough scores at the .
