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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Relapsing polychondritis associated with bilateral stapes footplate fixation: a case report | JOURNAL OF MEDICAL Sr CASE REPORTS Open Access Case report Relapsing polychondritis associated with bilateral stapes footplate fixation a case report Yohanna M Takwoingi Address Department of Otolaryngology Head and Neck Surgery City Hospital Dudley Road Birmingham UK Email YMT - Takwoingi@aol.com Received 29 December 2008 Accepted 27 May 2009 Published 9 September 2009 Journal ofMedical Case Reports 2009 3 8496 doi 10.4076 1752-1947-3-8496 This article is available from http jmedicalcasereports.com jmedicalcasereports article view 8496 2009 Takwoingi licensee Cases Network Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 3.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Relapsing polychondritis is a rare multisystem autoimmune disease of uncertain etiology characterized by recurrent episodes of inflammation and progressive destruction of cartilaginous tissues. Its respiratory cardiovascular renal and neurological complications are lifethreatening and it is thus important to recognize the disease and its complications early. Relapsing polychondritis may follow a slowly evolving or rapidly progressive course. Case presentation The case of a 39-years-old Caucasian woman with a three-year history of recurrent bilateral chondritis of the auricles nasal chondritis seronegative polyarthritis and dermatitis is reported. She had an associated bilateral stapedial fixation and one side was successfully operated on. She also had a large septal perforation involving both the cartilaginous and bony parts. The patient first presented with severe cutaneous inflammation when she was only one month old and so this is an illustrative case of relapsing polychondritis that slowly evolved over many years. Conclusions Relapsing polychondritis is still a relatively uncommon condition which explains