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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Avian myeoloblastosis virus (AMV): only one side of the coin. | Retrovirology BioMed Central Open Access Review Avian myeoloblastosis virus AMV only one side of the coin Bernard Perbal Address Department of Dermatology University of Michigan Medical School 1150 W. Medical Center Dr. Medical Science I Room 6447 Ann Arbor Michigan 48109-0609 USA Email Bernard Perbal - bperbal@free.fr Published 16 June 2008 Received 2 May 2008 Retrovirology 2008 5 49 doi 10.1186 1742-4690-5-49 Accepted 16 June 2008 This article is available from http www.retrovirology.cOm content 5 1 49 2008 Perbal licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ For many years scientists and suppliers have refered to AMV-RT as the reverse transcriptase produced by the Avian Myelobalstosis Virus. This manuscript briefly reviews the molecular basis for biological dependence of AMV for the envelope and RT proteins that are produced by its natural helper the Myeloblastosis Associated Virus MAV . Because the wide use of the term AMV RT obscures scientific facts it is worthwhile to clarify this issue for the scientific community especially for younger scientists who might not be aware of the functional relationships that exist between these two viruses. Background The Avian Myeloblastsis Virus AMV is well known among molecular biologists because AMV stocks have been used over several decades as one of the major source of avian Reverse Transcriptase RT . Originally identified from Rous Sarcoma Virus RSV 1 and Rauscher Leukaemia virus RLV 2 RT was also found to be an essential enzyme in the life cycle of other retroviruses and RNA viruses. The identification of RT with RNA-dependent DNA polymerase activities has enabled new developments in many .