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Hình 37.Sự xuất hiện của bỏng độ sâu thứ hai vết thương trên postburn 1 ngày. Ngài. 100. b Vào ngày 3 postburn, tế bào epidermic tiến triển vacuolation, sợi collagenous trong hạ bì trên bề mặt đã thoái hóa trong pha lê và các tế bào viêm rải rác xâm nhập vào trong lớp hạ bì. Ngài. | Fig. 37. a Appearance of deep second-degree burns wound on day 1 postburn. HE. X 100. b On day 3 postburn epidermic cells progressed to vacuolation collagenous fibers in superficial dermis had hyaline degeneration and scattered inflammatory cells infiltrated in dermis. HE. X 100. c On day 5 postburn superficial tissues in dermis were liquefactively necrotic and exfoliated. Inflammatory cells mainly neutrophil and occasionally with few macrophages infiltrated. HE. X 100. d On day 10 postburn the appearance of epithelia islands was seen. HE. X 100. e On day 10 postburn sweat glands in dermis proliferated with the infiltration of inflammatory cells all round mainly neutrophils as well as many lymphocytes and mononuclear macrophages. HE. X 100. f On day 15 postburn the adnexal epithelia in deep dermis grew vertically from the deep then migrated toward and covered the wounds. HE. X 100. g Most wounds were covered with stratified squamous epithelium. Actively proliferated fibroblasts and neoformative capillaries were visible in the dermis accompanied by the infiltration of lymphocytes. HE. X 100. h Neo-formative skin has an approximately normal structure. HE. X 100. when the necrotic epidermis exfoliated superficial tissue in the dermis liquefied and loosened due to necrosis and neutrophilic infiltration occasional lymphocyte and mononuclear macrophages fig. 37c . On day 7 postinjury the aforementioned pathological changes became more notable. On day 10 the superficial necrotic tissue in the dermis liquefied discharged and thinned. A large amount of neutrophils infiltrated into the liquefied necrotic tissue interwoven with few mononuclear macrophages. The dermal adnexal epithelia in the underlying Experimental and Clinical Study on Burns Regenerative Medicine and Therapy with MEBT MEBO 107 deep tissue revealed squamous metaplasia with enlarged cells deep karyon rich and red cytoplasm that clustered to form epithelium islands fig. 37d . Among these islands fibroblasts .
