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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Use of plasma C-reactive protein, procalcitonin, neutrophils, macrophage migration inhibitory factor, soluble urokinase-type plasminogen activator receptor, and soluble triggering receptor expressed on myeloid cells-1 in combination to diagnose infections: a prospective study. | Available online http ccforum.eom content 11 2 R38 Research Use of plasma C-reactive protein procalcitonin neutrophils macrophage migration inhibitory factor soluble urokinase-type plasminogen activator receptor and soluble triggering receptor expressed on myeloid cells-1 in combination to diagnose infections a prospective study Kristian Kofoed1 2 Ove Andersen1 2 Gitte Kronborg2 Michael Tvede3 Janne Petersen1 Jesper Eugen-Olsen1 and Klaus Larsen1 Clinical Research Unit Copenhagen University Hospital Hvidovre Kettegaard Allé 30 DK-2650 Hvidovre Denmark 2Department of Infectious Diseases Copenhagen University Hospital Kettegaard Allé 30 Hvidovre DK-2650 Hvidovre Denmark 3Department of Clinical Microbiology Copenhagen University Hospital Blegdamsvej 9 Rigshospitalet DK-2100 Copenhagen 0 Denmark Corresponding author Kristian Kofoed kristian.kofoed@hvh.regionh.dk Received 1 Dec 2006 Revisions requested 31 Jan 2007 Revisions received 21 Feb 2007 Accepted 16 Mar 2007 Published 16 Mar 2007 Critical Care 2007 11 R38 doi 10.1186 cc5723 This article is online at http ccforum.com content 11 2 R38 2007 Kofoed et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Accurate and timely diagnosis of community-acquired bacterial infections in patients with systemic inflammation remains challenging both for clinician and laboratory. Combinations of markers as opposed to single ones may improve diagnosis and thereby survival. We therefore compared the diagnostic characteristics of novel and routinely used biomarkers of sepsis alone and in combination. Methods This prospective cohort study included patients with systemic inflammatory response syndrome who were suspected of having community-acquired infections.