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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Gliomatosis cerebri presenting as rapidly progressive dementia and parkinsonism in an elderly woman: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Gliomatosis cerebri presenting as rapidly progressive dementia and parkinsonism in an elderly woman a case report Emmanuelle Duron Anne Lazareth Jean-Yves Gaubert Carole Raso Olivier Hanon and Anne-Sophie Rigaud Address Department of Geriatrics University René Descartes. Broca Hospital AP-HP France Email Emmanuelle Duron - emmanuelle.duron@brc.aphp.fr Anne Lazareth - lazarethanne@yahoo.fr Jean-Yves Gaubert - jean-yves.gaubert@brc.aphp.fr Carole Raso - carole.raso@brc.aphp.fr Olivier Hanon - olivier.hanon@brc.aphp.fr Anne-Sophie Rigaud - anne-sophie.rigaud@brc.aphp.fr Corresponding author Published 20 February 2008 Received 31 August 2007 Journal of Medical Case Reports 2008 2 53 doi 10.1186 1752-1947-2-53 Accepted 20 February 2008 This article is available from http www.jmedicalcasereports.cOm content 2 l 53 2008 Duron et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Dementia is one of the most important neurological disorders in the elderly. Dementia of tumoral origin is rare and parkinsonism of neoplastic origin is unusual. We herein report a case of gliomatosis cerebri a very rare brain tumor seldom affecting the elderly which presented as rapidly progressive dementia and parkinsonism. Case presentation An 82-year-old woman very rapidly developed progressive dementia and akineto-rigid parkinsonism. Brain CT scan was normal. Cerebral magnetic resonance imaging MRI with gadolinium injection highlighted a diffuse tumor-related infiltration involving both lobes the putamen the pallidum the substantia nigra and the brainstem corresponding to the specific description and definition of gliomatosis cerebri. Conclusion This atypical