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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Adult brain abscess associated with patent foramen ovale: a case report. | Journal of Medical Case Reports BioMed Central Case report Open Access Adult brain abscess associated with patent foramen ovale a case report Georgios T Stathopoulos Christina G Mandila Georgios V Koukoulitsios Nikodimos G Katsarelis Michel Pedonomos and Andreas Karabinis Address Intensive Care Unit General Hospital G. Gennimatas Athens Greece Email Georgios T Stathopoulos - gstathop@med.uoa.gr Christina G Mandila - xmandila@yahoo.com Georgios V Koukoulitsios - george97@hotmail.com Nikodimos G Katsarelis - eglax@hotmail.com Michel Pedonomos - eklax@hotmail.com Andreas Karabinis - akarab@ath.forthnet.gr Corresponding author Published 24 August 2007 Received 5 March 2007 Journal of Medical Case Reports 2007 1 68 doi 10.1186 1752-1947-1-68 Accepted 24 August 2007 This article is available from http www.jmedicalcasereports.cOm content 1 1 68 2007 Stathopoulos et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Brain abscess results from local or metastatic septic spread to the brain. The primary infectious site is often undetected more commonly so when it is distant. Unlike pediatric congenital heart disease minor intracardiac right-to-left shunting due to patent foramen ovale has not been appreciated as a cause of brain abscess in adults. Here we present a case of brain abscess associated with a patent foramen ovale in a 53-year old man with dental-gingival sepsis treated in the intensive care unit. Based on this case and the relevant literature we suggest a link between a silent patent foramen ovale paradoxic pathogen dissemination to the brain and development of brain abscess. Background One of the functions of the lung vasculature is to mechanically filter the blood hence right-to-left circulatory shunts can .