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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: A Systematic review of determinants of mortality in high frequency oscillatory ventilation in acute respiratory distress syndrome. | Available online http ccforum.eom content 10 1 R34 Research Systematic review of determinants of mortality in high frequency oscillatory ventilation in acute respiratory distress syndrome Casper W Bollen Cuno SPM Uiterwaal and Adrianus J van Vught University Medical Centre Utrecht The Netherlands Corresponding author Casper W Bollen c.w.bollen@umcutrecht.nl Received 19 Sep 2005 Revisions requested 9 Nov 2005 Revisions received 9 Dec 2005 Accepted 27 Jan 2006 Published 20 Feb 2006 Critical Care 2006 10 R34 doi 10.1186 cc4824 This article is online at http ccforum.com content 10 1 R34 2006 Lapinsky et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Mechanical ventilation has been shown to cause lung injury and to have a significant impact on mortality in acute respiratory distress syndrome. Theoretically high frequency oscillatory ventilation seems an ideal lung protective ventilation mode. This review evaluates determinants of mortality during use of high frequency oscillatory ventilation. Methods PubMed was searched for literature reporting randomized trials and cohort studies of high frequency ventilation in adult patients with acute respiratory distress syndrome. Data on mortality and determinants were extracted for patients treated with high frequency oscillatory ventilation. Linear regression analyses were conducted to produce graphical representations of adjusted effects of determinants of mortality. Results Cohorts of patients treated with high frequency oscillatory ventilation from two randomized trials and seven observational studies were included. Data from cohorts comparing survivors with non-survivors showed differences in age 42.3 versus 51.2 years prior time on conventional
