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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Cerebral perfusion pressure and brain ischaemia: can one size fit all? | Critical Care December 2005 Vol 9 No 6 Andrews Commentary Cerebral perfusion pressure and brain ischaemia can one size fit all Peter JD Andrews Reader in Anaesthesia Intensive Care University of Edinburgh Edinburgh UK Corresponding author Peter JD Andrews P.Andrews@ed.ac.uk Published online 22 November 2005 This article is online at http ccforum.Com content 9 6 638 2005 BioMed Central Ltd Critical Care 2005 9 638-639 DOI 10.1186 cc3922 See related research by Marin-Caballas et al. in this issue http ccforum.com content 9 6 R670 Abstract Current recommendations regarding the management of patients after traumatic brain injury include reduction in brain tissue pressure i.e. intracranial pressure and maintenance of an adequate arterial pressure these measures combined should result in cerebral perfusion pressure sufficient to achieve adequate oxygen delivery. After almost 20 years of observational studies comparing cerebral perfusion pressure and indices of cerebral oxygenation it is apparent that there is no single value for cerebral perfusion pressure that if achieved will provide adequate cerebral oxygen delivery in all patients. Traumatic brain injury remains a common problem and this should encourage researchers and clinicians to design better and adequately powered trials of monitors and associated interventions. In this issue of Critical Care Marin-Caballas and coworkers 1 investigate the relationship between cerebral perfusion pressure CPP and brain tissue oxygen tension PtiO2 . Identifying the optimal CPP following traumatic brain injury TBI is as crucial to best care for this vulnerable patient population as determining what is the best parameter with acceptable sensitivity and specificity for detecting impending brain ischaemia. Marin-Caballas and coworkers investigated the relationship between CPP and PtiO2 using an observational study design. The patients enrolled had suffered varying degrees of diffuse axonal injury and six of the 22 patients underwent .
