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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Bifidobacterium strains suppress in vitro the pro-inflammatory milieu triggered by the large intestinal microbiota of coeliac patients. | Journal of Inflammation BioMed Central Research Bifidobacterium strains suppress in vitro the pro-inflammatory milieu triggered by the large intestinal microbiota of coeliac patients Marcela Medina1 Giada De Palma1 Carmen Ribes-Koninckx2 Miguel Calabuig3 and Yolanda Sanz 1 Address 1Microbial Ecophysiology and Nutrition Instituto de Agroquímica y Tecnología de Alimentos CSIC Apartado 73 46100 Burjassot Valencia Spain 2Hospital Universitario La Fe Avenida Campanar 21 40009 Valencia Spain and 3Hospital General Universitario Avenida Tres Cruces s n 46014 Valencia Spain Email Marcela Medina - mmedina@iata.csic.es Giada De Palma - ciegia@iata.csic.es Carmen Ribes-Koninckx - ribes_car@gva.es Miguel Calabuig - calabuig_mig@gva.es Yolanda Sanz - yolsanz@iata.csic.es Corresponding author Open Access Published 3 November 2008 Received 27 July 2008 Accepted 3 November 2008 Journal of Inflammation 2008 5 19 doi 10.1186 1476-9255-5-19 This article is available from http www.journal-inflammation.com content 5 1 19 2008 Medina et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Coeliac disease CD is an enteropathy characterized by an aberrant immune response to cereal-gluten proteins. Although gluten peptides and microorganisms activate similar pro-inflammatory pathways the role the intestinal microbiota may play in this disorder is unknown. The purpose of this study was to assess whether the faecal microbiota of coeliac patients could contribute to the pro-inflammatory milieu characteristic of CD and the possible benefits of bifidobacteria. Methods The effect of faeces of 26 CD patients with active disease mean age 5.5 years range .
