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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Anti-inflammatory potential of a malleable matrix composed of fermented whey proteins and lactic acid bacteria in an atopic dermatitis model. | Journal of Inflammation BioMed Central Research Anti-inflammatory potential of a malleable matrix composed of fermented whey proteins and lactic acid bacteria in an atopic dermatitis model Josee Beaulieu1 2 Claude Dupont1 and Pierre Lemieux 2 Open Access Address Institut national de la recherche scientifique INRS-Institut Armand-Frappier 531 boul. des Prairies Laval Quebec Canada H7V 1B7 and 2Technologie Biolactis 500 boul. Cartier suite 218 Laval Quebec Canada H7V 5B7 Email Josee Beaulieu - josee.beaulieu@iaf.inrs.ca Claude Dupont - claude.dupont@iaf.inrs.ca Pierre Lemieux - plemieux@biolactis.com Corresponding author Published 21 March 2007 Received 9 June 2006 Accepted 21 March 2007 Journal of Inflammation 2007 4 6 doi l0.ll86 l476-9255-4-6 This article is available from http www.journal-inflammation.cOm content 4 1 6 2007 Beaulieu et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background Over the last 10 years whey proteins have received considerable attention in the area of functional foods and nutraceuticals. In this paper a novel fermented whey protein-based product described as a gel-like Malleable Protein Matrix MPM has been tested for its antiinflammatory activity. Preliminary in vitro results have already indicated that MPM could exert such an anti-inflammatory activity. Methods The systemic anti-inflammatory activity of the MPM was explored using the oxazolone-induced atopic contact dermatitis mouse model ACD . Parameters including ear thickness side effects as well as neutrophil extravasation were monitored. Results In the ACD model the MPM exhibited an anti-inflammatory effect comparable to that of hydrocortisone
