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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: Clinical review: Biphasic positive airway pressure and airway pressure release ventilation Christian Putensen1 and Hermann Wrigge2 for Anesthesiology and Intensive Care Medicine, Department of Anaesthesiology and Intensive Care . | Critical Care December 2004 Vol 8 No 6 Putensen and Wrigge Review Clinical review Biphasic positive airway pressure and airway pressure release ventilation Christian Putensen1 and Hermann Wrigge2 1 Professor for Anesthesiology and Intensive Care Medicine Department of Anaesthesiology and Intensive Care Medicine University of Bonn Bonn Germany 2Assistant Professor for Anesthesiology and Intensive Care Medicine Department of Anaesthesiology and Intensive Care Medicine University of Bonn Bonn Germany Corresponding author Christian Putensen putensen@uni-bonn.de Published online 2 August 2004 Critical Care 2004 8 492-497 DOI 10.1186 cc2919 This article is online at http ccforum.com content 8 6 492 2004 BioMed Central Ltd Abstract This review focuses on mechanical ventilation strategies that allow unsupported spontaneous breathing activity in any phase of the ventilatory cycle. By allowing patients with the acute respiratory distress syndrome to breathe spontaneously one can expect improvements in gas exchange and systemic blood flow based on findings from both experimental and clinical trials. In addition by increasing end-expiratory lung volume as occurs when using biphasic positive airway pressure or airway pressure release ventilation recruitment of collapsed or consolidated lung is likely to occur especially in juxtadiaphragmatic lung legions. Traditional approaches to mechanical ventilatory support of patients with acute respiratory distress syndrome require adaptation of the patient to the mechanical ventilator using heavy sedation and even muscle relaxation. Recent investigations have questioned the utility of sedation muscle paralysis and mechanical control of ventilation. Furthermore evidence exists that lowering sedation levels will decrease the duration of mechanical ventilatory support length of stay in the intensive care unit and overall costs of hospitalization. Based on currently available data we suggest considering the use of techniques of mechanical .
