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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Early Anti-inflammatory and anti-arthritic effects of yucca schidigera: A review. | Journal of Inflammation BioMed Central Review Open Access Anti-inflammatory and anti-arthritic effects of yucca schidigera A review PR Cheeke 1 2 S Piacente3 and W Oleszek4 Address department of Animal Sciences Oregon State University Corvallis OR 97333 USA 2Desert King International 7024 Manya Circle San Diego CA 92154 USA department of Pharmaceutical Sciences University of Salerno via Ponte Don Melillo-84084 Fisciano Salerno Italy and department of Biochemistry Institute of Soil Science and Plant Cultivation ul. Czartoryskich 8 24100 Pulawy Poland Email PR Cheeke - peter.r.cheeke@oregonstate.edu S Piacente - piacente@unisa.it W Oleszek - wo@sybilla.iung.pulawy.pl Corresponding author Published 29 March 2006 Received 16 November 2005 Accepted 29 March 2006 Journal of Inflammation2006 3 6 doi 10.1186 1476-9255-3-6 This article is available from http www.journal-inflammation.cOm content 3 1 6 2006Cheeke et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Yucca schidigera is a medicinal plant native to Mexico. According to folk medicine yucca extracts have anti-arthritic and anti-inflammatory effects. The plant contains several physiologically active phytochemicals. It is a rich source of steroidal saponins and is used commercially as a saponin source. Saponins have diverse biological effects including anti-protozoal activity. It has been postulated that saponins may have anti-arthritic properties by suppressing intestinal protozoa which may have a role in joint inflammation. Yucca is also a rich source of polyphenolics including resveratrol and a number of other stilbenes yuccaols A B C D and E . These phenolics have antiinflammatory activity. They are inhibitors of the nuclear transcription factor NFkappaB. NFkB