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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Endotoxin neutralization and anti-inflammatory effects of tobramycin and ceftazidime in porcine endotoxin shock. | Available online http ccforum.eom content 8 1 R35 Research Open Access Endotoxin neutralization and anti-inflammatory effects of tobramycin and ceftazidime in porcine endotoxin shock Gunilla Goscinski1 Miklos Lipcsey2 Mats Eriksson3 Anders Larsson4 Eva Tano5 and Jan Sjolin6 1MD Section of Infectious Diseases Department of Medical Sciences Uppsala University Hospital Uppsala Sweden 2MD Department of Anesthesiology and Intensive Care Gavle-Sandviken County Hospital Gavle Sweden 3Associate Professor Section of Anesthesiology Intensive Care Department of Surgical Sciences Uppsala University Hospital Uppsala Sweden 4Associate Professor Section of Clinical Chemistry Department of Medical Sciences Uppsala University Hospital Uppsala Sweden 5Biomedical Scientist Section of Clinical Microbiology Department of Medical Sciences Uppsala University Hospital Uppsala Sweden 6Associate Professor Section of Infectious Diseases Department of Medical Sciences Uppsala University Hospital Uppsala Sweden Correspondence Gunilla Goscinski gunilla.goscinski@medicin.uas.lul.se Received 2 June 2003 Revisions requested 11 July 2003 Revisions received 7 November 2003 Accepted 25 November 2003 Published 23 December 2003 Critical Care 2004 8 R35-R41 DOI 10.1186 cc2415 This article is online at http ccforum.com content 8 1 R35 2004 Goscinski et al. licensee BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X . This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Introduction Antibiotics used for treatment of severe bacterial infections have been shown to exert effects on the inflammatory response in addition to their antibacterial effects. The aim of the present study was to investigate whether the biological effects of endotoxin in a porcine model could be neutralized by tobramycin and whether tobramycin or ceftazidime was able to .