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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về y học đề tài:Introducing Critical Care’s ongoing reviews of science. | Available online http ccforum.eom content 6 6 461 Editorial Introducing Critical Carets ongoing reviews of science Delbert R Dorscheid1 and Keith R Walley2 Assistant Professor Respirology and Critical Care Medicine McDonald Research Laboratories St Paul s Hospital University of British Columbia Vancouver Canada 2Professor of Medicine and Critical Care Medicine McDonald Research Laboratories St Paul s Hospital University of British Columbia Vancouver Canada Correspondence Delbert R Dorscheid DDorscheid@mrl.ubc.ca Published online 9 October 2002 Critical Care 2002 6 461 DOI 10.1186 cc1833 This article is online at http ccforum.com content 6 6 461 2002 BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract The explosion in biomedical research and the use of computers to access and disseminate ideas has increased our knowledge but has also strikingly shortened the time for new concepts to move from initial basic science discovery to clinical application. In fact there are more new discoveries than anyone can reasonably stay abreast of. Critical Care has therefore launched a series of articles using the knowledge and judgement of experts at the leading edge to bring the most exciting novel basic science concepts with the greatest potential for clinical impact to our readership. Keywords critical care science Three billion DNA base pairs 50 000 genes twice as many splice variant mRNA transcripts and a further magnification of possible protein products due to post-translational processing let n be the number of different products lead to n n factorial e.g. 7 7 X 6 X 5 X 4 X 3 X 2 X 1 possible interactions. This explosion in biomedical information coupled with the use of computers to access and disseminate ideas has increased our knowledge but has also strikingly shortened the time for new concepts to move from initial basic science discovery to clinical application. Sequencing of the genome means that a review of DNA sequences measuring mRNA expression and
