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Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú yđề tài: Adaptation of mammalian host-pathogen interactions in a changing arctic environment. | Hueffer et al. Acta Veterinaria Scandinavica 2011 53 17 http www.actavetscand.eom content 53 1 17 AVS ACTAVETERINARIA Sco Anov cc a SCANDINAVICA REVIEW Open Access Adaptation of mammalian host-pathogen interactions in a changing arctic environment Karsten Hueffer1 2 Todd M O Hara1 2 Erich H Follmann2 Abstract Many arctic mammals are adapted to live year-round in extreme environments with low winter temperatures and great seasonal variations in key variables e.g. sunlight food temperature moisture . The interaction between hosts and pathogens in high northern latitudes is not very well understood with respect to intra-annual cycles seasons . The annual cycles of interacting pathogen and host biology is regulated in part by highly synchronized temperature and photoperiod changes during seasonal transitions e.g. freezeup and breakup . With a warming climate only one of these key biological cues will undergo drastic changes while the other will remain fixed. This uncoupling can theoretically have drastic consequences on host-pathogen interactions. These poorly understood cues together with a changing climate by itself will challenge host populations that are adapted to pathogens under the historic and current climate regime. We will review adaptations of both host and pathogens to the extreme conditions at high latitudes and explore some potential consequences of rapid changes in the Arctic. Introduction We review the current knowledge on arctic mammalian hosts pathogens and climate change from the epidemiologic triad perspective Host - Pathogen - Environment . These complex interactions require better understanding to develop conceptual models and possible predictive mechanisms that impact wildlife and public health zoonoses management for a changing arctic environment. Temperature and photoperiod changes are major cues regulating extreme biological changes during the annual cycle for many arctic resident mammals most notably at seasonal transitions during spring and