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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Airway pressure release ventilation increases cardiac performance in patients with acute lung injury/adult respiratory distress syndrome. | Available online http ccforum.eom content 5 4 221 Research article Airway pressure release ventilation increases cardiac performance in patients with acute lung injury adult respiratory distress syndrome Lewis J Kaplan 1- Heatherlee Bailey1 and Vincent Formosa Medical College of PA-Hahnemann University Department of Surgery Philadelphia Pennsylvania USA department of Emergency Medicine Medical College of PA-Hahnemann University Philadelphia Pennsylvania USA Department of Pulmonary Critical Care Medical College of PA-Hahnemann University Philadelphia Pennsylvania USA Correspondence Lewis J Kaplan Lewis.Kaplan@drexel.edu Received 5 August 1999 Revisions requested 16 September 1999 Revisions received 26 January 2001 Accepted 8 May 2001 Published 3 July 2001 Critical Care 2001 5 221-226 2001 Kaplan et al licensee BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract Background The purpose of the present study is to determine whether airway pressure release ventilation APRV can safely enhance hemodynamics in patients with acute lung injury ALI and or adult respiratory distress syndrome ARDS relative to pressure control ventilation PCV . Methods Patients with severe acute lung injury or ARDS who were managed with inverse-ratio pressure control ventilation neuromuscular blockade and a pulmonary artery catheter were switched to APRV. Hemodynamic performance as well as pressor and sedative needs was assessed after discontinuing neuromuscular blockade Results Mean age was 58 9 years n 12 and mean Lung Injury Score was 7.6 2.1. Temperature and arterial oxygen tension fractional inspired oxygen FiO2 were similar among the patients. Peak airway pressures fell from 38 3 for PCV to 25 3 cmH2O for APRV and mean pressures fell from 18 3 for PCV to 1 2 2 cmH2O for APRV. Paralytic use and sedative use were significantly lower with APRV than with PCV. Pressor use decreased substantially with ARPV. Lactate levels remained normal but decreased on APRV. Cardiac index .
