Đang chuẩn bị liên kết để tải về tài liệu:
Dermal Absorption and Toxicity Assessment

Since this book was first published in 1998, there have been significant advances in our understanding of the morphology of the skin and the properties that govern the transport of molecules into and across the three major strata. The multitude of data that has been generated has allowed the development of predictive models for both the rate and extent of dermal absorption and has increased our ability to predict the likelihood of local toxic events subsequent to solute penetration and permeation. In this second edition we have completely revised and updated many of the chapters that appeared in the earlier version and we have expanded the scope. | DRUGS AND THE PHARMACEUTICAL SCIENCES VOLUME 177 Dermal Absorption and Toxicity Assessment Second Edition Vehicle Drug Intercellular Dermis Stratum corneum Viable epidermis Subcutaneous tissue Shunts Metabolism Blood vessel Deep tissue penetration edited by Michael s. Roberts Kenneth A. Walters informa healthcare Dermal Absorption and Toxicity Assessment DRUGS AND THE PHARMACEUTICAL SCIENCES A Series of Textbooks and Monographs Executive Editor James Swarbrick PharmaceuTech Inc. Pinehurst North Carolina Advisory Board Larry L. Augsburger University of Maryland Baltimore Maryland Jennifer B. Dressman University of Frankfurt Institute of Pharmaceutical Technology Frankfurt Germany Anthony J. Hickey University of North Carolina School of Pharmacy Chapel Hill North Carolina Ajaz Hussain Sandoz Princeton New Jersey Joseph W. Polli GlaxoSmithKline Research Triangle Park North Carolina Stephen G. Schulman University of Florida Gainesville Florida Yuichi Sugiyama University of Tokyo Tokyo Japan Geoffrey T. Tucker University of Sheffield Royal Hallamshire Hospital Sheffield United Kingdom Harry G. Brittain Center for Pharmaceutical Physics Milford New Jersey Robert Gurny Universite de Geneve Geneve Switzerland Jeffrey A. Hughes University of Florida College of Pharmacy Gainesville Florida Vincent H. L. Lee US FDA Center for Drug Evaluation and Research Los Angeles California Kinam Park Purdue University West Lafayette Indiana Jerome P. Skelly Alexandria Virginia Elizabeth M. Topp University of Kansas Lawrence Kansas Peter York University of Bradford School of Pharmacy Bradford United .