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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Infective endocarditis: too ill to be operated? | Critical Care April 2002 Vol 6 No 2 Rubinovitch and Pittet Commentary Infective endocarditis too ill to be operated Bina Rubinovitch and Didier Pittet Research Associate Infection Control Program Department of Internal Medicine University of Geneva Hospitals Switzerland Director of Infection Control Program Department of Internal Medicine University of Geneva Hospitals Switzerland Correspondence Didier Pittet didier.pittet@hcuge.ch Published online 12 March 2002 Critical Care 2002 6 106-107 2002 BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract Infective endocarditis remains a disease associated with high mortality in certain groups of patients with death resulting primarily from central nervous system complications and congestive heart failure. Combined medical and surgical therapy reduces both early and late mortality in complicated cases especially in patients with valvular dysfunction related to heart failure. In these patients heart failure is the strongest indication for valve replacement. There are no consensus indications for surgery however in the presence of neurological complications or multiple organ failure. Limited data suggest that such surgery is feasible even in complicated cases necessitating admission to the intensive care unit and carries an acceptable risk for in-hospital mortality. It is important that critically ill patients with infective endocarditis are enrolled into multicenter studies using adequate severity scoring systems to assess the impact of clinical and imaging variables on patients outcome. Until such data are obtained clinical judgement is still the best tool in decision-making regarding the individual patient. Keywords decision-making infective endocarditis neurological complications valve replacement Infective endocarditis IE has remained a prevalent disease in general hospitals with a fairly constant incidence over the past 30 years accounting for one case per 1000 hospital admissions range 0.38-1.24 per