Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ
Tải xuống
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:Primary ciliary dyskinesia. | Available online http respiratory-research.eom content 2 5 E001 Meeting report Primary ciliary dyskinesia a report from ATS 2001 May 18-23 San Francisco Peadar G Noone Pulmonary Research and Treatment Center Department of Medicine University of North Carolina at Chapel Hill USA Correspondence Peadar G Noone MD Pulmonary Division CB 7248 The University of North Carolina at Chapel Hill Chapel Hill NC 27599-7248 USA. Tel 1 919 966 1077 fax 1 919 966 7524 e-mail pnoone@med.unc.edu Received 29 May 2001 Accepted 13 June 2001 Published 22 June 2001 Respir Res 2001 2 E001 2001 BioMed Central Ltd Print ISSN 1465-9921 Online ISSN 1465-993X Abstract Primary ciliary dyskinesia PCD is a genetic disorder of abnormal ciliary structure and function that leads to defective mucociliary clearance resulting in oto-sino-pulmonary disease and infertility. The disease is currently under intense investigation by a number of research groups worldwide. At the recent American Thoracic Society meeting in San Francisco in May 2001 two sessions focused on PCD a symposium session on May 21 with several featured expert speakers was followed by a mini-symposium on Tuesday May 22 with one featured speaker and presentation of nine abstracts covering a range of research topics. Mattias Salathe University of Miami USA and Stephen Brody Washington University St Louis USA chaired the symposium session. Presentations focused on the clinical spectrum of PCD the genetics of PCD a proteomics approach to detail the structure of cilia the role of cilia in the embryology of situs laterality and airway epithelial cell biology. The mini-symposium was chaired by Peadar Noone University of North Carolina USA and Malcolm King University of Alberta USA and included presentations on the use of PCD as a human disease model accurate definition of the phenotype using clinical and cell biologic markers and molecular studies. The latter reports ranged from isolation of a protein involved in ciliary structure and function
