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Tham khảo luận văn - đề án 'báo cáo y học: "high-grade endometrial stromal sarcoma presenting in a 28-year-old woman during pregnancy: a case report"', luận văn - báo cáo phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả | Amant et al. Journal of Medical Case Reports 2010 4 243 http www.jmedicalcasereports.eom content 4 1 243 jAg JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access High-grade endometrial stromal sarcoma presenting in a 28-year-old woman during pregnancy a case report 1 1 2 1 3 Frédéric Amant Kristel Van Calsteren Maria Debiec-Rychter Liesbeth Heyns Katya Op De Beeck Xavier Sagaert4 Bart Bollen5 Ignace Vergote1 Abstract Introduction To the best of our knowledge soft tissue sarcomas have not prevously been reported as a complication during pregnancy. Case presentation A 28-year-old Caucasian woman was diagnosed with a transperitoneal sarcoma during pregnancy. Morphological immunohistochemical chromosomal and mutational analyses pointed towards a highgrade endometrial stromal sarcoma. Although surgery and chemotherapy are possible during pregnancy we were unable to perform these in this case. Conclusion The potential to treat gynecological cancer during pregnancy should always be assessed individually. Introduction Recent literature shows an increased interest in cancer complicating pregnancy. This is a result of the realization that oncological treatment modalities including surgery and chemotherapy can be applied after the first gestational trimester without hampering the fetus 1 2 . Evidence from western countries shows that mainly breast cancer and hematological malignancies are diagnosed during pregnancy 3 . Gynecological cancers also significantly contribute to the problem. Cancer of the cervix is the second most common cancer among women worldwide and the most common gynecological cancer in the developing world 4 . Incidence rates of cancer complicating pregnancy therefore vary around the world. Especially with this perspective in mind guidelines for the treatment of gynaecological cancer were recently proposed 5 . In contrast sarcomas are uncommon and increase with age. Apart from bone sarcomas we are not aware of other sarcomas complicating pregnancy. .
