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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: Inflammation in sputum relates to progression of disease in subjects with COPD: a prospective descriptive study. | Respiratory Research BioMed Central Open Access Inflammation in sputum relates to progression of disease in subjects with COPD a prospective descriptive study David G Parr1 Andrew J White2 Darren L Bayley3 Peter J Guest4 and Robert A Stockley 3 Address Department of Respiratory Medicine University Hospitals of Coventry and Warwickshire Clifford Bridge Road Coventry CV2 2DX UK 2Department of Respiratory Medicine Gloucester Royal Infirmary Gloucester UK 3Lung Investigation Unit University Hospital of Birmingham Edgebaston Birmingham B15 2TH UK and 4Department of Radiology Queen Elizabeth Hospital Edgebaston Birmingham B15 2TH UK Email David G Parr - david.parr@uhcw.nhs.uk Andrew J White - andrew.white@glos.nhs.uk Darren L Bayley - bayleydl@hotmail.com Peter J Guest-peter.guest@uhb.nhs.uk Robert A Stockley - r.a.stockley@bham.ac.uk Corresponding author Published 18 November 2006 Received 20 July 2006 Accepted 18 November 2006 Respiratory Research 2006 7 136 doi 10.1186 1465-9921-7-136 This article is available from http respiratory-research.com content 7 1 136 2006 Parr et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Inflammation is considered to be of primary pathogenic importance in COPD but the evidence on which current understanding is based does not distinguish between cause and effect and no single mechanism can account for the complex pathology. We performed a prospective longitudinal study of subjects with COPD that related markers of sputum inflammation at baseline to subsequent disease progression. Methods A cohort of 56 patients with chronic bronchitis was characterized in the stable state at baseline and after
