Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ
Tải xuống
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Waist circumference as the predominant contributor to the micro-inflammatory response in the metabolic syndrome: a cross sectional study. | Rogowski et al. Journal of Inflammation 2010 7 35 http www.journal-inflammation.eom content 7 1 35 JOURNAL OF INFLAMMATION RESEARCH Open Access Waist circumference as the predominant contributor to the micro-inflammatory response in the metabolic syndrome a cross sectional study 1.2 t 1.2t 1.2 1.2 1.2 1.2 Ori Rogowski Itzhak Shapira Orit Kliuk-Ben Bassat Tamar Chundadze Talya Finn Shlomo Berliner Arie Steinvil1 2 Abstract Background The metabolic syndrome MetS is associated with the presence of low grade inflammation. Our aim was to analyze the inter-relations between each of the components of the metabolic syndrome MetS and four inflammatory markers namely high sensitivity C-reactive protein hs-CRP the erythrocyte sedimentation rate the concentration of fibrinogen and the white blood cell count. Methods We have analyzed data collected between September 2002 and June 2009 in the Tel-Aviv medical center inflammation survey TAMCIS . We recruited both apparently healthy individuals and individuals presenting with atherothrombotic risk factors. All participants were enrolled during their routine annual health check-up and gave their written informed consent. This is a cross sectional study in which we have fitted linear regression models using inflammatory markers as the dependant variables and adjust them according to the different components of the MetS and multiple other confounders. Results Included were 12 072 individuals of whom there were 7 760 men at a mean S.D. age of 44 11 years and 4 312 women aged 44 11 years. A significant correlation was noted between most components of the MetS and all inflammatory markers the most significant one being with hs-CRP. In the multi-adjusted regression analysis waist was the factor that best explained the variability of hs-CRP in both women and men. It also remained a significant variable for the other inflammatory markers. Conclusions From amongst the various components of the MetS waist circumference appears to exert the .
