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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Weekly self-monitoring and treatment adjustment benefit patients with partly controlled and uncontrolled asthma: an analysis of the SMASHING study. | van der Meer et al. Respiratory Research 2010 11 74 http respiratory-research.eom content 11 1 74 RESPIRATORY RESEARCH RESEARCH Open Access Weekly self-monitoring and treatment adjustment benefit patients with partly controlled and uncontrolled asthma an analysis of the SMASHING study Victor van der Meer 1 2 Henk F van Stel1 Moira J Bakker1 Albert C Roldaan3 Willem JJ Assendelft2 Peter J Sterk4 Klaus F Rabe5 Jacob K Sont1 5 for the SMASHING Self-Management of Asthma Supported by Hospitals ICT Nurses and General practitioners Study Group Abstract Background Internet-based self-management has shown to improve asthma control and asthma related quality of life but the improvements were only marginally clinically relevant for the group as a whole. We hypothesized that selfmanagement guided by weekly monitoring of asthma control tailors pharmacological therapy to individual needs and improves asthma control for patients with partly controlled or uncontrolled asthma. Methods In a 1-year randomised controlled trial involving 200 adults 18-50 years with mild to moderate persistent asthma we evaluated the adherence with weekly monitoring and effect on asthma control and pharmacological treatment of a self-management algorithm based on the Asthma Control Questionnaire ACQ . Participants were assigned either to the Internet group n 101 that monitored asthma control weekly with the ACQ on the Internet and adjusted treatment using a self-management algorithm supervised by an asthma nurse specialist or to the usual care group UC n 99 . We analysed 3 subgroups patients with well controlled ACQ 0.75 partly controlled 0.75 ACQ 1.5 or uncontrolled ACQ 1.5 asthma at baseline. Results Overall monitoring adherence was 67 95 CI 60 to 74 . Improvements in ACQ score after 12 months were -0.14 p 0.23 -0.52 p 0.001 and -0.82 p 0.001 in the Internet group compared to usual care for patients with well partly and uncontrolled asthma at baseline respectively. Daily inhaled corticosteroid dose .