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TB remains an important and serious global public health challenge that requires coordinated international and national prevention and control efforts. Although the incidence of TB in Canada is low and the disease is no longer common in the general population, TB remains a serious problem in certain sub-populations, such as First Nations and Inuit, persons living in Canada who have arrived from regions of the world with a high incidence of TB and those with other health problems such as HIV/AIDS. The many and varied conditions in which Canadians live mean that the risks and impacts of TB are not uniformly distributed within our boundaries. There is a. | Operations Directorate Health Branch Immigration Medical Examination Instructions Tuberculosis Subject Instructions for the screening of clients to detect tuberculosis TB in the context of the Canadian immigration medical examination IME . Goal Objective These instructions are provided to ensure that Panel Physicians PPs follow a consistent and appropriate process in the following Identification of clients with active or latent pulmonary or extra-pulmonary TB Investigation of clients where there is clinical suspicion of active pulmonary TB Investigation of clients who are close contacts of an individual with active TB Referral to a specialist e.g. TB Control for further investigation and treatment of suspected active TB and latent TB and Completion and grading of an IME of a client with suspected tuberculosis. Instructions Rationale TB remains an important and serious global public health challenge that requires coordinated international and national prevention and control efforts. Although the incidence of TB in Canada is low and the disease is no longer common in the general population TB remains a serious problem in certain sub-populations such as First Nations and Inuit persons living in Canada who have arrived from regions of the world with a high incidence of TB and those with other health problems such as HIV AIDS. The many and varied conditions in which Canadians live mean that the risks and impacts of TB are not uniformly distributed within our boundaries. There is a pressing need to better understand and target groups at increased risk and tailor prevention and control efforts to meet their specific needs. In addition resistance to some of the drugs used to treat TB is a growing problem in some locations. In a globalized interconnected world the implications of drugresistant strains are a concern for all nations. Keeping in mind the Global Plan to Stop TB 2006-2015 the overarching goal is now of reducing the national incidence rate of reported TB in .