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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Psychological distress of patients suffering from restless legs syndrome: a cross-sectional study | Scholz et al. Health and Quality of Life Outcomes 2011 9 73 http www.hqlo.eom content 9 1 73 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Psychological distress of patients suffering from restless legs syndrome a cross-sectional study I_I s u . u . s c r z I 7 11_I z I lzz D z I . 2 C ri I I_I s L 3 I I I z z D Z X Z t Z X I 4 D I T 1 S z 5 Z l ft ỉ Z t Z l z I s I_I z r r y lz 1 Hanna Scholz Heike Denes Svenja Happe Juergen Bengel naif KOhnen ana Magaoina Hornyak Abstract Background Restless legs syndrome RLS is a chronic disorder with substantial impact on quality of life similar to that seen in diabetes mellitus or osteoarthritis. Little is Known about the psychological characteristics of RLS patients although psychological factors may contribute to unfavourable treatment outcome. Methods In an observational cross-sectional design we evaluated the psychological features of 166 consecutive RLS patients from three outpatient clinics by means of the Symptom Checklist 90-R SCL-90-R questionnaire. Additionally the Beck Depression Inventory-II BDI-II and the International RLS Severity Scale IRLS were measured. Both treated and untreated patients were included all patients sought treatment. Results Untreated patients n 69 had elevated but normal scores on the SCL-90-R Global Severity Index GSI p 0.002 and on the sub-scales somatisation p 0.001 compulsivity p 0.003 depression p 0.02 and anxiety p 0.004 compared with a German representative sample. In the treated group particularly in those patients who were dissatisfied with their actual treatment n 62 psychological distress was higher than in the untreated group with elevated scores for the GSI p 0.03 and the sub-scales compulsivity p 0.006 depression p 0.012 anxiety p 0.031 hostility p 0.013 phobic anxiety p 0.024 and paranoid ideation p 0.012 . Augmentation the most serious side effect of dopaminergic i.e. first-line treatment of RLS and loss of efficacy were accompanied with the highest psychological .
