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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds | Lara et al. Journal of Nanobiotechnology 2011 9 30 http www.jnanobiotechnology.eom content 9 1 30 JOURNAL OF NANOBIOTECHNOLOGY REVIEW Open Access Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds Humberto H LaraH Elsa N Garza-Trevino2t Liliana Ixtepan-Turrent2 and Dinesh K Singh1 Abstract The advance in nanotechnology has enabled us to utilize particles in the size of the nanoscale. This has created new therapeutic horizons and in the case of silver the currently available data only reveals the surface of the potential benefits and the wide range of applications. Interactions between viral biomolecules and silver nanoparticles suggest that the use of nanosystems may contribute importantly for the enhancement of current prevention of infection and antiviral therapies. Recently it has been suggested that silver nanoparticles AgNPs bind with external membrane of lipid enveloped virus to prevent the infection. Nevertheless the interaction of AgNPs with viruses is a largely unexplored field. AgNPs has been studied particularly on HIV where it was demonstrated the mechanism of antiviral action of the nanoparticles as well as the inhibition the transmission of HIV-1 infection in human cervix organ culture. This review discusses recent advances in the understanding of the biocidal mechanisms of action of silver Nanoparticles. Keywords Silver Nanoparticles Virucides Bactericides HIV AIDS Antibacterial agents Review Historically silver metal has been used widely across the civilizations for different purposes. Many societies use silver as jewelry ornamentation and fine cutlery. Silver jewelry wares and cutlery was considered to impart health benefits to the users. In ancient Indian medical system Ayurveda silver has been described as therapeutic agent for many diseases. There is an increasing use of silver as an efficacious antibacterial and antifungal agent in wound care products and medical devices 1-4 including dental work and catheters 5-7 . .
