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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Validation of a computer-adaptive test to evaluate generic health-related quality of life | Rebollo et al. Health and Quality of Life Outcomes 2010 8 147 http www.hqlo.eom content 8 1 147 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Validation of a computer-adaptive test to evaluate generic health-related quality of life 1 l Z-.- 1l Z-1 1 2 1 Pablo Rebollo Ignacio Castejon Jesus Cuervo Guillermo Villa Eduardo García-Cueto Helena Diaz-Cuervo Pilar C Zardain1 José Muniz2 Jordi Alonso3 4 the Spanish CAT-Health Research Group Abstract Background Health Related Quality of Life HRQoL is a relevant variable in the evaluation of health outcomes. Questionnaires based on Classical Test Theory typically require a large number of items to evaluate HRQoL. Computer Adaptive Testing CAT can be used to reduce tests length while maintaining and in some cases improving accuracy. This study aimed at validating a CAT based on Item Response Theory IRT for evaluation of generic HRQoL the CAT-Health instrument. Methods Cross-sectional study of subjects aged over 18 attending Primary Care Centres for any reason. CATHealth was administered along with the SF-12 Health Survey. Age gender and a checklist of chronic conditions were also collected. CAT-Health was evaluated considering 1 feasibility completion time and test length 2 content range coverage Item Exposure Rate IER and test precision and 3 construct validity differences in the CAT-Health scores according to clinical variables and correlations between both questionnaires. Results 396 subjects answered CAT-Health and SF-12 67.2 females mean age SD 48.6 17.7 years. 36.9 did not report any chronic condition. Median completion time for CAT-Health was 81 seconds IQ range 59-118 and it increased with age p 0.001 . The median number of items administered was 8 IQ range 6-10 . Neither ceiling nor floor effects were found for the score. None of the items in the pool had an IER of 100 and it was over 5 for 27.1 of the items. Test Information Function TIF peaked between levels -1 and 0 of HRQoL. Statistically significant .
