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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Validation of the Excited Component of the Positive and Negative Syndrome Scale (PANSSEC) in a naturalistic sample of 278 patients with acute psychosis and agitation in a psychiatric emergency room | Montoya et al. Health and Quality of Life Outcomes 2011 9 18 http www.hqlo.eom content 9 1 18 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Validation of the Excited Component of the Positive and Negative Syndrome Scale PANSS-EC in a naturalistic sample of 278 patients with acute psychosis and agitation in a psychiatric emergency room Alcviocc cviorcvx o 1A rri f cll cc l croc I I lie I IvW2 I I lie c.in3 fcdihvi i- rpk jr4 incl Cil in P -72 Alonso Montoya Ampaio valladaies Luis Lizdn Luis San Rodligo Escobai dĩ Id Silvia raz Abstract Background Despite the wide use of the Excited Component of the Positive and Negative Syndrome Scale PANSS-EC in a clinical setting to assess agitated patients a validation study to evaluate its psychometric properties was missing. Methods Data from the observational NATURA study were used. This research describes trends in the use of treatments in patients with acute psychotic episodes and agitation seen in emergency departments. Exploratory principal component factor analysis was performed. Spearman s correlation and regression analyses linear regression model as well as equipercentile linking of Clinical Global Impression of Severity CGI-S Agitation and Calmness Evaluation Scale ACES and PANSS-EC items were conducted to examine the scale s diagnostic validity. Furthermore reliability Cronbach s alpha and responsiveness were evaluated. Results Factor analysis resulted in one factor being retained according to eigenvalue 1. At admission the PANSS-EC and CGI-S were found to be linearly related with an average increase of 3.4 points p 0.001 on the PANSS-EC for each additional CGI-S point. The PANSS-EC and ACES were found to be linearly and inversely related with an average decrease of 5.5 points p 0.001 on the PANSS-EC for each additional point. The equipercentile method shows the poor sensitivity of the ACES scale. Cronbach s alpha was 0.86 and effect size was 1.44. Conclusions The factorial analyses confirm the .
