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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Multi-modality curative treatment of salivary gland cancer liver metastases with drug-eluting bead | Karatzas et al. Journal of Medical Case Reports 2011 5 416 http www.jmedicalcasereports.eom content 5 1 416 JOURNALOF medical Ur Case REPORTS CASE REPORT Open Access Multi-modality curative treatment of salivary gland cancer liver metastases with drug-eluting bead chemoembolization radiofrequency ablation and surgical resection a case report 1 2 3 1 Andreas Karatzas Konstantinos Katsanos loannis Maroulis Christina Kalogeropoulou Evaggelos Tzorakoleftherakis3 and Dimitris Karnabatidis2 Abstract Introduction Liver metastases are rare in salivary gland tumors and have been reported only once to be the first manifestation of the disease. They are usually treated with surgical resection of the primary tumor and systemic chemotherapy. Drug-eluting bead chemoembolization has an evolving role in the treatment of hepatocellular carcinoma as well as in the treatment of metastatic disease of the liver. Nevertheless it has never been used in a patient with salivary gland liver metastases. Case presentation We report a case of a 51-year-old Caucasian Greek woman who presented to our hospital with liver metastases as the first manifestation of an adenoid cystic carcinoma of the left submandibular gland. The liver lesions were deemed inoperable because of their size and multi-focality and proved resistant to systemic chemotherapy. She was curatively treated with a combination of doxorubicin eluting bead DC Beads chemoembolization intra-operative and percutaneous radiofrequency ablation and radiofrequency-assisted surgical resection. The patient remained disease-free one year after the surgical resection. Conclusion In conclusion this complex case is an example of inoperable liver metastatic disease from the salivary glands that was refractory to systemic chemotherapy but was curatively treated with a combination of locoregional therapies and surgery. A multi-disciplinary approach and the adoption of modern radiological techniques produced good results after conventional therapies
