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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Adherence with urate-lowering therapies for the treatment of gout. | Available online http arthritis-research.eom content 11 2 R46 Open Access Research article Adherence with urate-lowering therapies for the treatment of gout Leslie R Harrold1 2 3 Susan E Andrade1 2 3 Becky A Briesacher1 2 Marsha A Raebel3 4 Hassan Fouayzi1 Robert A Yood1 5 and Ira S Ockene2 Department of Medicine the Meyers Primary Care Institute 425 North Lake Avenue Worcester MA 01 605 USA 2Department of Medicine University of Massachusetts Medical School 377 Plantation Street Worcester MA 01605 USA 3The HMO Research Network Center for Education and Research in Therapeutics Department of Medicine University of Massachusetts Medical School 377 Plantation Street Worcester MA 01605 USA 4Department of Research Kaiser Permanente Colorado Institute for Health Research PO Box 378066 Denver CO 80237-8066 USA 5Department of Medicine Fallon Clinic 425 North Lake Avenue Worcester MA 01605 USA Corresponding author Leslie R Harrold Leslie.Harrold@umassmed.edu Received 17 Nov 2008 Revisions requested 7 Jan 2009 Revisions received 5 Feb 2009 Accepted 27 Mar 2009 Published 27 Mar 2009 Arthritis Research Therapy 2009 11 R46 doi 10.1186 ar2659 This article is online at http arthritis-research.com content 11 2 R46 2009 Harrold et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Adherence to urate-lowering drugs ULDs has not been well evaluated among those with gout. Our aim was to assess the level and determinants of non-adherence with ULDs prescribed for gout. Methods We identified persons using two integrated delivery systems aged 18 years or older with a diagnosis of gout who initiated use of allopurinol probenecid or sulfinpyrazone from 1 January 2000 to 30 June 2006. Non-adherence was measured using the .