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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Distinct effects of rectum delineation methods in 3D-confromal vs. IMRT treatment planning of prostate cancer. | Radiation Oncology BioMed Central Research Distinct effects of rectum delineation methods in 3D-confromal vs IMRT treatment planning of prostate cancer Matthias Guckenberger Jurgen Meyer Kurt Baier Dirk Vordermark and Michael Flentje Open Access Address Department of Radiation Oncology University of Wuerzburg Josef-Schneider-Str. 11 97080 Wuerzburg Germany Email Matthias Guckenberger - Guckenberg_M@klinik.uni-wuerzburg.de Jurgen Meyer - Meyer_J@klinik.uni-wuerzburg.de Kurt Baier - Baier_K@klinik.uni-wuerzburg.de Dirk Vordermark - Vordermark_D@klinik.uni-wuerzburg.de Michael Flentje - Flentje_M@klinik.uni-wuerzburg.de Corresponding author Published 06 September 2006 Radiation Oncology 2006 1 34 doi l0.ll86 l748-7l 7X-1-34 Received 27 July 2006 Accepted 06 September 2006 This article is available from http www.ro-journal.cOm content l l 34 2006 Guckenberger et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The dose distribution to the rectum delineated as solid organ rectal wall and rectal surface in 3D conformal 3D-CRT and intensity-modulated radiotherapy treatment IMRT planning for localized prostate cancer was evaluated. Materials and methods In a retrospective planning study 3-field 4-field and IMRT treatment plans were analyzed for ten patients with localized prostate cancer. The dose to the rectum was evaluated based on dose-volume histograms of I the entire rectal volume DVH 2 manually delineated rectal wall DWH 3 rectal wall with 3 mm wall thickness DWH3 4 and the rectal surface DSH . The influence of the rectal filling and of the seminal vesicles anatomy on these dose parameters was investigated. A literature review of the dose-volume relationship for late rectal toxicity was conducted. .
