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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: "Radiation-induced cancer after radiotherapy for non-Hodgkin's lymphoma of the head and neck: a retrospective study. | Radiation Oncology BioMed Central Research Radiation-induced cancer after radiotherapy for non-Hodgkin s lymphoma of the head and neck a retrospective study KazumaToda 1 Hitoshi Shibuya1 Keiji Hayashi1 and Fumio Ayukawa2 Address Department of Radiology Tokyo Medical and Dental University 5-45 Yushima 1-chome Bunkyo-ku Tokyo 113-8519 Japan and 2Department of Radiology Niigata Cancer Center Hospital Niigata Japan Email KazumaToda - tdmrad@tmd.ac.jp Hitoshi Shibuya - shubuya.mrad@tmd.ac.jp Keiji Hayashi - hysmrad@tmd.ac.jp Fumio Ayukawa - ayukawa@yahoo.co.jp Corresponding author Open Access Published 10 July 2009 Received 17 March 2009 Radiation Oncology 2009 4 21 doi 10.1186 1748-717X-4-21 Accepted 10 July 2009 This article is available from http www.ro-journal.cOm content 4 1 21 2009 Toda et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background survivors of non-Hodgkin s lymphoma NHL are well known to be at an increased risk of second malignancies. In this study we evaluated the incidence and clinical features of head and neck cancer HNC occurring after radiotherapy RT for NHL. Materials and methods We investigated the clinical records of 322 patients who had received RT for early-stage NHL of the head and neck at our institute between 1952 and 2000. Results There were 4 patients with a second HNC developing in the irradiated field consisting of 2 patients with gum cancer 1 case with tongue cancer and 1 case with maxillary sinus cancer. The pathological diagnosis in all the 4 patients was squamous cell carcinoma SCC . Two of the patients one with gum cancer and one with maxillary sinus cancer died of the second HNC while the remaining 2 patients are still living at the time of writing after therapy for the .
