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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus: implications in the pathogenesis of septic arthritis and other soft tissue infections. | Available online http arthritis-research.eom content 8 6 R1 76 Open Access Research article Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus implications in the pathogenesis of septic arthritis and other soft tissue infections Siva Kanangat1 2 Arnold Postlethwaite1 2 Karen Hasty1 2 3 Andrew Kang1 2 Mark Smeltzer4 Whitney Appling1 and Dennis Schaberg1 5 Department of Medicine University of Tennessee Health Science Center 956 Court Avenue Memphis TN 38163 USA 2Veterans Affairs Medical Center 1 030 Jefferson Avenue Research 151 Memphis TN 381 04 USA department Orthopedic Surgery University of Tennessee Health Science Center 956 Court Avenue Memphis TN 38163 USA department of Microbiology Immunology University of Arkansas Medical School 4301 W. Markham Street 511 Little Rock AR 72205 USA 5Greater Los Angeles Healthcare 111 11301 Wilshire Boulevard Los Angeles CA 90073 USA Corresponding author Siva Kanangat skanangat@utmem.edu Received 16 Aug 2006 Revisions requested 11 Sep 2006 Revisions received 18 Oct 2006 Accepted 27 Nov 2006 Published 27 Nov 2006 Arthritis Research Therapy 2006 8 R176 doi 10.1186 ar2086 This article is online at http arthritis-research.com content 8 6 R176 2006 Kanangat et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Infections of body tissue by Staphylococcus aureus are quickly followed by degradation of connective tissue. Patients with rheumatoid arthritis are more prone to S. aureus-mediated septic arthritis. Various types of collagen form the major structural matrix of different connective tissues of the body. These different collagens are degraded by specific matrix metalloproteinases MMPs produced by fibroblasts other .
