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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Microcirculation abnormalities in patients with fibromyalgia – measured by capillary microscopy and laser fluxmetry. | Available online http arthritis-research.eom content 7 2 R209 Research article Microcirculation abnormalities in patients with fibromyalgia -measured by capillary microscopy and laser fluxmetry Susanne Morf1 Beatrice Amann-Vesti2 Adrian Forster1 Ulrich K Franzeck3 Renate Koppensteiner3 Daniel Uebelhart1 and Haiko Sprott1 Open Access Department of Rheumatology Institute of Physical Medicine University Hospital Zurich Switzerland department of Medicine Division of Vascular Medicine Angiology University Hospital Zurich Switzerland 3Center for Vascular Diseases Zurich Switzerland Corresponding author Haiko Sprott haiko.sprott@usz.ch Received 7 May 2004 Revisions requested 27 May 2004 Revisions received 1 Oct 2004 Accepted 11 Oct 2004 Published 10 Dec 2004 Arthritis Res Ther 2005 7 R209-R216 DOI 10.1186 ar1459 2004 Morf et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is cited. Abstract This unblinded preliminary case-control study was done to demonstrate functional and structural changes in the microcirculation of patients with primary fibromyalgia FM . We studied 10 women 54.0 3.7 years of age with FM diagnosed in accordance with the classification criteria of the American College of Rheumatology and controls in three groups n 10 in each group - age-matched women who were healthy or who had rheumatoid arthritis or systemic scleroderma SSc . All 40 subjects were tested within a 5-week period by the same investigators using two noninvasive methods laser fluxmetry and capillary microscopy. The FM patients were compared with the healthy controls negative controls and with rheumatoid arthritis patients and SSc patients positive controls . FM patients had fewer capillaries in the nail fold P 0.001 and significantly more capillary dilatations P .