Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ
Tải xuống
Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Prevalence of Helicobacter pylori in HIV-infected, HAART-naïve Ugandan children: a hospital-based survey | Hestvik et al. Journal of the International AIDS Society 2011 14 34 http www.jiasociety.Org content 14 1 34 JOURNALOF THE INTERNATIONAL AIDS SOCIETY RESEARCH Open Access Prevalence of Helicobacter pylori in HIV-infected HAART-naive Ugandan children a hospital-based survey 1.2 1.2 1.3 5 2 3 Elin Hestvik 1 Thorkild Tylleskar1 Grace Ndeezi 1 Lena Grahnquist Edda Olafsdottir James K Tumwine and Deogratias H Kaddu-Mulindwa4 Abstract Background The aim of this survey was to determine the prevalence of and factors associated with Helicobacter pylori H. pylori colonization in HIV-infected highly active antiretroviral therapy-naive Ugandan children aged 0-12 years. Methods In a hospital-based survey 236 HIV-infected children were tested for H. pylori colonization using a faecal antigen test. A standardized interview with socio-demographic information and medical history was used to assess risk factors. A cluster of differentiation 4 CD4 cell percentage was prevalent in most children. Results The overall prevalence of H. pylori in the HIV-infected children was 22.5 . Age-specific prevalence was as follows up to one year 14.7 1-3 years 30.9 and 3-12 years 20.7 . HIV-infected children who were more seriously affected by their disease low CD4 cell percentage or WHO clinical stage II-IV were less likely to be colonized with H. pylori. There was a trend for a lower prevalence of H. pylori in children who had taken antibiotics for the preceding two weeks 21.6 than in those who had not taken antibiotics 35.7 . There was no statistically significant difference in prevalence by gender housing congested living education of the female caretaker drinking water or toilet facilities. Conclusions HIV-infected HAART-naive Ugandan children had a lower prevalence of H. pylori colonization compared with apparently healthy Ugandan children 44.3 . Children with a low CD4 cell percentage and an advanced clinical stage of HIV had an even lower risk of H. pylori colonization. Treatment with .