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The life cycle of the retrovirus consist of several steps. It begins with the binding of the viral envelope to cellular receptors, which enables fusion of the viral envelope with the cellular membrane. Consequently, the viral particle is uncoated, liberating the viral core into the cell cytoplasm. The viral DNA is reverse transcribed to DNA. Then, the viral DNA is transported to the nucleus where it is integrated into the host cell’s genome. From there, viral DNA is transcribed to RNA, some of which is translated to proteins. The viral RNA is packed in a viral particle along with viral proteins. Then, virion is produced when. | REGENERATIVE MEDICINE AND TISSUE ENGINEERING - CELLS AND BIOMATERIALS Edited by Daniel Eberli INTECHWEB.ORG Regenerative Medicine and Tissue Engineering - Cells and Biomaterials Edited by Daniel Eberli Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2011 InTech All chapters are Open Access articles distributed under the Creative Commons Non Commercial Share Alike Attribution 3.0 license which permits to copy distribute transmit and adapt the work in any medium so long as the original work is properly cited. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published articles. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Romina Krebel Technical Editor Teodora Smiljanic Cover Designer Jan Hyrat Image Copyright Arun K. Sharma 2011. First published August 2011 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Regenerative Medicine and Tissue Engineering - Cells and Biomaterials Edited by Daniel Eberli p. cm. ISBN 978-953-307-663-8 IkfTE IJ OPEN ACCESS INI Lvrl PUBLISHER INTECH open free online editions of InTech Books and Journals can be found at .
