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Selection of chemical markers is crucial for the quality control of herbal medicines, including authentication of genuine species, harvesting the best quality raw materials, evaluation of post- harvesting handling, assessment of intermediates and finished products, and detection of harmful or toxic ingredients. Ideal chemical markers should be the therapeutic components of herbal medicines. However, for most herbal medicines, the therapeutic components have not been fully elucidated or easily monitored. Bioactive, characteristic, main, synergistic, correlative, toxic and general components may be selected. This article reviews the effective use of chemical markers in the quality control of herbal medicines including the selection criteria considering the roles and physicochemical factors which. | Chinese Medicine BioMed Central Open Access Review Chemical markers for the quality control of herbal medicines an overview Songlin Li Quanbin Han Chunfeng Qiao Jingzheng Song Chuen Lung Cheng and Hongxi Xu Address Chinese Medicine Laboratory Hong Kong Jockey Club Institute of Chinese Medicine Hong Kong SAR PR China Email Songlin Li - slli@hkjcicm.org Quanbin Han - qbhan@hkjcicm.org Chunfeng Qiao - cfqiao@hkjcicm.org Jingzheng Song - jzsong@hkjcicm.org Chuen Lung Cheng - andrewch@hkjcicm.org Hongxi Xu - xuhongxi@hkjcicm.org Corresponding author Published 28 June 2008 Chinese Medicine 2008 3 7 doi 10.1186 1749-8546-3-7 Received 8 March 2008 Accepted 28 June 2008 This article is available from http www.cmjournal.Org content 3 1 7 2008 Li et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Selection of chemical markers is crucial for the quality control of herbal medicines including authentication of genuine species harvesting the best quality raw materials evaluation of postharvesting handling assessment of intermediates and finished products and detection of harmful or toxic ingredients. Ideal chemical markers should be the therapeutic components of herbal medicines. However for most herbal medicines the therapeutic components have not been fully elucidated or easily monitored. Bioactive characteristic main synergistic correlative toxic and general components may be selected. This article reviews the effective use of chemical markers in the quality control of herbal medicines including the selection criteria considering the roles and physicochemical factors which may affect the effective use of chemical markers. Background Herbal .
