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Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Malignant phyllodes tumor with heterologous liposarcomatous differentiation and tubular adenoma-like epithelial component. | Int. J. Med. Sci. 2006 3 130 Case Report International Journal of Medical Sciences ISSN 1449-1907 www.medsci.org 2006 3 4 130-134 2006 Ivyspring International Publisher. All rights reserved Malignant phyllodes tumor with heterologous liposarcomatous differentiation and tubular adenoma-like epithelial component L. Uriev 1 I. Maslovsky 2 P. Vainshtein 3 B. Yoffe 3 D. Ben-Dor 1 1. Institute of Pathology Barzilai Medical Center Ashkelon Israel 2. Department of Internal Medicine Barzilai Medical Center Ashkelon Israel 3. Department of General and Vascular Surgery Barzilai Medical Center Ashkelon Israel Correspondence to Dr. Igor Maslovsky phone 972-8-8558048 fax 972-8-8558057 email igorgn@012.net.il or igorgn@barzi.health.gov.il Received 2006.03.20 Accepted 2006.07.21 Published 2006.08.15 Phyllodes tumor of the breast is a biphasic fibroepithelial neoplasm. A 30-year-old woman presented with a 1year history of a palpable asymptomatic right breast mass without axillary lymphadenopathy and family history of breast carcinoma. Malignant phyllodes tumor was diagnosed. The authors present not previously described histological appearance of this tumor where an epithelial component was identical to that of a tubular adenoma of the breast with the review of the literature. This is in addition to very rare liposarcomatous stromal differentiation in the malignant phyllodes tumor. Key words phyllodes tumor liposarcoma tubular adenoma 1. Introduction Phyllodes tumors are rare entity in the breast. They make up less than 1 of all breast tumors 1 . The majority of these lesions behave in a completely benign fashion in that they do not have metastatic potential leaving local recurrence as the only real concern. Local recurrence per se is not an indicator of malignancy because it has been described in benign borderline and malignant phyllodes tumors. Phyllodes tumors are characterized by a combination of hypercellular stroma and cleft-like or cystic spaces lined by epithelium into which
